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Passive transfer of immunity against hepatic amoebiasis in the hamster by cells
Author(s) -
GHADIRIAN E.,
MEEROVITCH E.
Publication year - 1983
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1111/j.1365-3024.1983.tb00752.x
Subject(s) - hamster , immunity , amoebiasis , biology , immunology , spleen , mesocricetus , effector , immune system , cellular immunity , endocrinology
Summary The role of passive cell‐mediated transfer of immunity in hepatic amoebiasis in hamsters was studied. The transfer of peritoneal cells from hamsters vaccinated against or protected from hepatic amoebiasis and from those with hepatic amoebiasis, as well as of spleen cells from vaccinated or protected, but not from infected hamsters, conferred immunity against hepatic amoebiasis in recipient normal hamsters. Treatment of the spleen cells from protected hamsters with anti T‐cell serum abolished their ability to transfer immunity. It appears that the effector mechanism in this system is T‐cell dependent.