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CRYSTALLINE AGGREGATES OF PROTEIN‐GLYCOGEN COMPLEXES (ALIAS ‘VIRUS‐LIKE PARTICLES’) IN SKELETAL MUSCLE: REPORT OF A CASE AND REVIEW OF THE LITERATURE
Author(s) -
PALMUCCI L.,
ANZIL A. P.,
LUH S.
Publication year - 1983
Publication title -
neuropathology and applied neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.538
H-Index - 95
eISSN - 1365-2990
pISSN - 0305-1846
DOI - 10.1111/j.1365-2990.1983.tb00324.x
Subject(s) - glycogen , skeletal muscle , chemistry , muscle biopsy , biopsy , anatomy , biology , biochemistry , pathology , medicine
Palmucci L., Anzil A.P. & Luh S. (1983) Neuropathology and Applied Neurobiology 9, 61–71 Crystalline aggregates of protein‐glycogen complexes (alias ‘viruslike particles’) in skeletal muscle: report of a case and review of the literature Crystalline arrays of so‐called ‘virus‐like particles’ were found in postmortem samples of skeletal muscle obtained from an 11‐month‐old female infant. In a large number of skeletal muscle fibres crystalline inclusions were abundant, variously configurated and positively stained with a cytochemical method for polysaccharides. A battery of enzymatic tests, including some with diastase and a‐amylase, was, however, entirely non‐contributory. A muscle biopsy studied 5 months before death had disclosed no crystalline inclusions of any kind. The literature concerning similar cases of ‘virus‐like particles’, crystalline glycogen aggregates or protein‐glycogen complexes in muscle is reviewed. Possible reasons underlying the aggregation of protein‐glycogen complexes into crystalline arrays are discussed.