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ELECTRON MICROSCOPIC OBSERVATIONS ON MALIGNANT CHOROID PLEXUS PAPILLOMA
Author(s) -
MOSS T. H.
Publication year - 1983
Publication title -
neuropathology and applied neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.538
H-Index - 95
eISSN - 1365-2990
pISSN - 0305-1846
DOI - 10.1111/j.1365-2990.1983.tb00110.x
Subject(s) - choroid plexus , choroid plexus papilloma , pathology , basement membrane , biopsy , papilloma , anatomy , cilium , ultrastructure , electron microscope , choroid , medicine , biology , retina , microbiology and biotechnology , central nervous system , physics , neuroscience , optics , endocrinology
Biopsy material from two cases of histologically proven malignant choroid plexus papilloma was studied by electron microscopy. Both tumours differed from benign papillomas in showing poorly differentiated areas with numerous mitoses. Even in such areas, however, a number of ultrastructural features characteristic of normal choroid plexus tissue were observed in both the cases, including cilia, microvilli, a continuous basement membrane and capillary endothelial fenestration. Such findings may be helpful in establishing the primary origin of malignant tumours in the choroid plexus, especially where light microscopy of poorly differentiated biopsy samples makes diagnosis uncertain.