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MYELIN BASIC PROTEIN AND GLIAL FIBRILLARY ACIDIC PROTEIN IN HUMAN FETAL BRAIN*
Author(s) -
BORIT A.,
McINTOSH G. C.
Publication year - 1981
Publication title -
neuropathology and applied neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.538
H-Index - 95
eISSN - 1365-2990
pISSN - 0305-1846
DOI - 10.1111/j.1365-2990.1981.tb00099.x
Subject(s) - glial fibrillary acidic protein , myelin basic protein , gfap stain , immunostaining , astrocyte , myelin , pathology , biology , neuroglia , immunohistochemistry , central nervous system , neuroscience , medicine
We demonstrated myelin basic protein (MBP) and glial fibrillary acidic protein (GFAP) in tissue sections of routinely‐processed premature human brain employing the peroxidase‐antiperoxidase (PAP) method. The MBP immunostain delineated oligodendroglia before the appearance of myelin sheaths. The GFAP immunostain indicated that in addition to the stellate astrocyte, bouquet‐shaped glia and radial glia are also astrocytic in nature. The bouquet‐shaped glia may be the normal counterpart for the gemistocytic astrocyte. The glia limitans stained with GFAP beginning with our first specimen. Small numbers of ependymal cells also contained cytoplasmic. GFAP.