Premium
NEUROGLIA IN THE INTERNAL GRANULAR LAYER OF THE DEVELOPING RAT CEREBELLAR CORTEX
Author(s) -
LEWIS P. D.,
FüLÖP Z.,
HAJÓS F.,
BALÁZS R.,
WOODHAMS P. L.
Publication year - 1977
Publication title -
neuropathology and applied neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.538
H-Index - 95
eISSN - 1365-2990
pISSN - 0305-1846
DOI - 10.1111/j.1365-2990.1977.tb00582.x
Subject(s) - cerebellum , cerebellar cortex , granular layer , neuroglia , population , biology , cortex (anatomy) , neuroscience , cerebral cortex , cell division , anatomy , central nervous system , cell , medicine , genetics , environmental health
Neuroglia in the internal granular layer of the developing rat cerebellar cortex In the first week after birth, a proliferating cell population identifiable as astrocytes is a prominent constituent of the developing internal granular Layer of the rat cerebellar cortex. This population becomes less prominent in the second postnatal week, and by 12 days proliferation within it has fallen to a low level. At 6 days, the dividing astrocytes of the internal granular layer have a cell cycle time of 19.5 h and an estimated turnover time of between 36 and 72 h. These figures are comparable to those obtained for other proliferating cell populations in the 6 day old brain, and contrast with previously published data suggesting much slower rates of neuroglial division in the early postnatal cerebellum.