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Scintigraphic validation of AC Biosusceptometry to study the gastric motor activity and the intragastric distribution of food in humans
Author(s) -
Américo M. F.,
Oliveira R. B.,
Romeiro F. G.,
Baffa O.,
Corá L. A.,
Miranda J. R. A.
Publication year - 2007
Publication title -
neurogastroenterology and motility
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.489
H-Index - 105
eISSN - 1365-2982
pISSN - 1350-1925
DOI - 10.1111/j.1365-2982.2007.00960.x
Subject(s) - stomach , scintigraphy , medicine , motor activity , contractility , nuclear medicine , gastroenterology
Abnormal intragastric distribution of food (IDF) and a phasic contractility in the proximal stomach have been related to dyspeptic symptoms. Thus, the behaviour of the stomach and the proximal region, in particular, continues to attract attention and demand for reliable and comfortable techniques. The aims of this study were to employ AC Biosusceptometry (ACB) and scintigraphy to evaluate IDF and gastric motor activity in humans. Fifteen healthy volunteers ingested 60 mL of yogurt containing 2 mCi of 99m Tc and 4 g of ferrite. Each volunteer had gastric motility and IDF evaluated twice on separate days; on one occasion by ACB and another by scintigraphy. Digital signal processing was performed in MatLab (Mathworks Inc., Natick, MA, USA). Results were expressed as mean ± SD. Similar results of distal accumulation time ( P < 0.001) were obtained for scintigraphy (6.93 ± 3.25 min) and for ACB (7.04 ± 3.65 min). Fast Fourier Transform revealed two dominant frequencies ( P > 0.9). Besides the well‐know frequency of 3 cpm, our results showed identical frequencies in proximal stomach recordings ( P < 0.001) for scintigraphic (1.01 ± 0.01 cpm) and ACB (0.98 ± 0.06 cpm). In summary, our data showed that scintigraphy and ACB are promising techniques to evaluate several aspects of gastric motility. Moreover, ACB is non‐invasive, radiation‐free and deserves the same importance as conventional methods for this kind of analysis.