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Gastric electrical stimulation and sacral electrical stimulation: are two devices better than one?
Author(s) -
JAIN S,
ALJUBURI A,
BRIZZOLORA J,
SECREST CL,
WHITE P,
ABELL TL
Publication year - 2006
Publication title -
neurogastroenterology and motility
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.489
H-Index - 105
eISSN - 1365-2982
pISSN - 1350-1925
DOI - 10.1111/j.1365-2982.2006.00789_45.x
Subject(s) - gastroparesis , medicine , nausea , bloating , vomiting , genitourinary system , abdominal pain , urinary system , stimulation , anesthesia , surgery , gastric emptying , stomach
Gastric Electrical Stimulation (GES) is available as a Humanitarian Use Device for patients with the symptoms of gastroparesis and is effective in reducing gastrointestinal symptoms. We have previously shown that patients with gastric motor disorders often have co‐existing abnormalities of the genitourinary system (Gastroenterol 112: A737, 1997), which may now be treated with sacral electrical stimulation (SES), resulting in similar improvements in genitourinary symptoms. Patients: We compared the results of therapy with GES and SES in 13 patients who were implanted with both devices. Patients were 11 f, 2 m, mean age of 41 years, who had documented gastroparesis as well as bladder or other pelvic floor dysfunction. All 13 patients had received their GES before the SES. Methods: Patients were evaluated at baseline and latest follow up (median 4 years for GES and 2 years for SES), according to previously standardized scores of GI (GI: 0–4, TSS max 20) and GU (GU: 0–3, UTSS, max 12) function. Results were compared by paired t‐tests and reported as mean ± SE. Results: All 13 patients improved both GI and GU symptoms and the improvement in all parameters as nausea, vomiting, anorexia, bloating, abdominal pain and gastric total symptom score (TSS), leakage, urgency, voiding difficulty, number of pads used and urinary total symptom score (UTSS) were statistically significant (see table below). Conclusions: The combination of GES and SES appears to be both safe and effective for patients with con‐comitant gastroparesis and bladder dysfunction and the existence of a stimulator for one disorder does not preclude another stimulator.Vomiting Nausea Anorexia Bloating Abd. Pain TSSBefore 2.75 ± 0.62 3.96 ± 0.13 3.46 ± 1.08 3.57 ± 0 3.79 ± 0.11 16.00 ± 1.05 After 0.63 ± 0.18 1.03 ± 0.07 1.63 ± 0.07 1.89 ± 0.36 1.29 ± 0.25 6.64 ± 0.94 P.Value <0.001 <0.001 <0.001 <0.002 <0.001 <0.001Leakage Urgency Voiding Difficulty #Pads UTSSBefore 1.33 ± 0.49 2.0 ± 0.51 2.43 ± 0.43 0.83 ± 0.48 6.5 ± 1.28 After 0 0.67 ± 0.42 0.5 ± 0.31 0 1.4 ± 0.75 P.Value <0.001 0.007 0.002 0.007 <0.001