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Ambulatory oesophageal pressure, pH and ECG recording in patients with normal and pathological coronary angiography and intermittent chest pain
Author(s) -
LUX G.,
ELS I.,
THE G. S.,
BOZKURT T.,
ORTH K. H.,
BEHRENBECK D.
Publication year - 1995
Publication title -
neurogastroenterology and motility
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.489
H-Index - 105
eISSN - 1365-2982
pISSN - 1350-1925
DOI - 10.1111/j.1365-2982.1995.tb00205.x
Subject(s) - medicine , chest pain , cardiology , pathological , ambulatory , radiology , angiography , coronary angiography , myocardial infarction
The present study was performed to compare pain‐related oesophageal motility, gastro‐oesophageal reflux and ST‐segment deviations in patients with intermittent chest pain and normal or pathological coronary angiography. Thirty patients (11 males, 19 females; mean age 54.8 years) with normal and 15 patients (12 males, 3 females; mean age 66.7 years) with pathological coronary angiography were investigated by 24‐h oesophageal pressure, pH and ECG recording. Chest pain correlated with motility abnormalities or gastro‐oesophageal reflux occurred in 33% (10/30) of patients with normal coronary arteries and in 26% of patients with pathological coronary angiography. Symptomatic and asymptomatic ST‐segment changes were less frequently observed in patients with normal angiography (4/30) than in patients with pathological coronary angiography (7/14; P = 0.02). Oesophageal dysfunction coincided with ST‐segment deviation in 6.7% (2/30) of patients with normal and 40% (6/15) of patients with pathological coronary angiography (P = 0.02). The conclusions reached were: (1) pain‐correlated abnormal motility or gastro‐oesophageal reflux occurred in patients with normal and pathological coronary angiography at the same frequency; (2) ambulatory motility and pH recording alone does not appear to differentiate between cardiac and non‐cardiac chest pain; (3) simultaneous ECG recording reveals a significant correlation of ST‐segment deviation and gastro‐oesophageal reflux or abnormal motility in patients with coronary artery stenosis.