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Influence of Stress on Gastric Emptying Depends on the Nature of Meals, Stressors, and Animal Species
Author(s) -
Gué M.,
Fioramonti J.,
Buéno L.
Publication year - 1990
Publication title -
neurogastroenterology and motility
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.489
H-Index - 105
eISSN - 1365-2982
pISSN - 1350-1925
DOI - 10.1111/j.1365-2982.1990.tb00003.x
Subject(s) - gastric emptying , meal , medicine , saline , endocrinology , zoology , stomach , chemistry , biology
This work evaluated the effects of 20‐minute exposures to acoustic stress, cold (10°C), or immobilization on gastric emptying of test meals containing 51 Cr sodium chromate in rats and mice. Four diets were studied: one consisting of reconstituted cow's milk (diet A), a synthetic diet containing arabic gum, glucose, and casein (diet B), diet B with arachis oil (diet C), and a nonnutritive diet containing methylcellulose and saline (diet D). Test‐meal volumes were 0.5 ml in mice and 3 ml in rats. Gastric emptying, expressed as percentage of meal emptied, was measured 30 minutes after gavage with the test meal. Acoustic stress and cold, applied after gavage, increased (p > .05) the rate of gastric emptying of diet A by 46.8% and 70.7%, respectively, in mice and by 13.4% and 22.0% in rats. Immobilization did not affect (p > .05) the gastric emptying of diet A in either species. Cold significantly increased (p ≤ .05) the emptying rate of diets C and D in mice but not in rats. Gastric emptying of diet D was unaffected by the three stressors in mice but was increased (45.7%) by cold in rats. This study shows that the effects of stress on gastric emptying of a nutritive meal depend mainly on the type of stressor. Of the three tested, cold was the most powerful. These results also support the conclusion that stressor, diet, and species are all important in gastric emptying.