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Social networking between mobile introns and their host genes
Author(s) -
Stoddard Barry,
Belfort Marlene
Publication year - 2010
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.2010.07217.x
Subject(s) - biology , host (biology) , mobile genetic elements , intron , gene , genetics , computational biology , evolutionary biology , genome
Summary Homing endonucleases have long been known as the orchestrators of intron mobility. However, the extent of their influence on the intron and its genetic and cellular environment is still being elucidated. The accompanying paper emphasizes the importance of temporal control of endonuclease expression on splicing, expression of the host gene and cellular metabolism, while it raises questions to guide future inquiry.