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Archaeal transcription and its regulators
Author(s) -
Geiduschek E. Peter,
Ouhammouch Mohamed
Publication year - 2005
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.2005.04627.x
Subject(s) - biology , rna polymerase ii , transcription (linguistics) , eukaryotic transcription , genetics , rna polymerase , transcription factor ii d , general transcription factor , transcription factor ii b , computational biology , rna polymerase ii holoenzyme , polymerase , transcription factor ii a , archaea , rna , promoter , gene , gene expression , linguistics , philosophy
Summary The relatively complex archaeal RNA polymerases are constructed along eukaryotic lines, and require two initiation factors for promoter recognition and specific transcription that are homologues of the RNA polymerase II TATA‐binding protein and TFIIB. Many archaea also produce histones. In contrast, the transcriptional regulators encoded by archaeal genomes are primarily of bacterial rather than eukaryotic type. It is this combination of elements commonly regarded as separate and mutually exclusive that promises unifying insights into basic transcription mechanisms across all three domains of life.