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Development of the cell‐division site in FtsA ‐ filaments
Author(s) -
Cook William R.,
Rothfield Lawrence I.
Publication year - 1994
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.1994.tb02184.x
Subject(s) - cytokinesis , biology , cell division , plasmolysis , division (mathematics) , microbiology and biotechnology , biophysics , cell , botany , genetics , cell wall , arithmetic , mathematics
Summary Early changes at cell‐division sites were studied in non‐septate filaments induced by growth of fts ATs mutant cells under non‐permissive conditions. The positions of localized regions of plasmolysis were used as markers for the locations of partial and complete annular structures that are thought to be precursors of the periseptal annuli that flank the septum during cytokinesis. The results confirmed that these structures were localized at potential division sites and suggested a model in which older division sites play a role in the generation of new sites for future use, with each older site being used only once for this purpose. The results also suggest that the details of division‐site development can profitably be studied in cells in which early events in the differentiation process are uncoupled from the septation event.