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Influence of pH on bacterial gene expression
Author(s) -
Olson Eric R.
Publication year - 1993
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.1993.tb01198.x
Subject(s) - biology , gene , transcription (linguistics) , virulence , bacteria , translation (biology) , gene expression , function (biology) , adaptation (eye) , genetics , mechanism (biology) , regulation of gene expression , amino acid , microbiology and biotechnology , chromosomal translocation , biochemistry , messenger rna , philosophy , linguistics , epistemology , neuroscience
Summary Bacteria respond to changes in internal and external pH by adjusting the activity and synthesis of proteins associated with many different processes, including proton translocation, amino acid degradation, adaptation to acidic or basic conditions and virulence. While, for many of these examples, the physiological and biological consequence of the pH‐induced response is clear, the mechanism by which the transcription/translation machinery is signalled is not. These examples are discussed along with several others in which the function of the gene or protein remains a mystery.