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Energy requirements for protein translocation across the Escherichia coli inner membrane
Author(s) -
Geller B. L.
Publication year - 1991
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.1991.tb02138.x
Subject(s) - biology , escherichia coli , transmembrane protein , inner membrane , membrane protein , escherichia coli proteins , chromosomal translocation , atpase , membrane , membrane transport protein , biophysics , biochemistry , microbiology and biotechnology , enzyme , gene , receptor
Summary Both ATP and an electrochemical potential play roles in translocating proteins across the Inner membrane of Escherichia coli. Recent discoveries have dissected the overall transmembrane movement into separate subreactions with different energy requirements, identified a translocation ATPase, and reconstituted both energy‐requiring steps of the reaction from purified components. A more refined understanding of the energetics of this fundamental process is beginning to provide answers about the basic issues of how proteins move across the hydrophobic membrane barrier.