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Yeast genes involved in DNA‐repair processes: new looks on old faces
Author(s) -
Friedberg E. C.
Publication year - 1991
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.1991.tb02074.x
Subject(s) - biology , saccharomyces cerevisiae , yeast , gene , dna , genetics , dna damage , dna repair
Summary Multiple genes (many of which are designated RAD (for rad iation resistance)) are required for cellular responses to DNA damage in the yeast Saccharomyces cerevisiae. In recent years a number of these genes have been cloned and sequenced and in some cases their polypeptide products have been purified and characterized biochemically. These studies are beginning to yield clues about the possible nature of the multiple biochemical pathways for DNA‐damage processing in yeast.