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The ami locus of the Gram‐positive bacterium Streptococcus pneumoniae is similar to binding protein‐dependent transport operons of Gram‐negative bacteria
Author(s) -
Alloing G.,
Trombe M.C,
Claverys J.P.
Publication year - 1990
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.1990.tb00632.x
Subject(s) - biology , operon , permease , escherichia coli , streptococcus pneumoniae , bacteria , microbiology and biotechnology , locus (genetics) , homology (biology) , protein subunit , enterobacteriaceae , gene , genetics
Summary The complete nucleotide sequence of the ami locus of Streptococcus pneumoniae revealed the presence of six open reading frames, amiABCDEF. The predicted Ami proteins are probably involved in a transport system. The Ami A, C, D, E, and F proteins exhibit homology with components of the oligopeptide permeases ( opp ) of Salmonella typhimurium and Escherichia coli. Intriguingly, the AmiB protein is homologous to ArsC, a cytosolic modifier subunit of the anion pump encoded by the arsenical resistance operon of the R‐factor R773 from E. coli. Data are presented which indicate that Ami is indeed a transport system.