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Multiple promoters control the regulation of the Pseudomonas aeruginosa regA gene
Author(s) -
Storey D. G.,
Frank D. W.,
Farinha M. A.,
Kropinski A. M.,
Iglewski B. H.
Publication year - 1990
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.1990.tb00616.x
Subject(s) - promoter , biology , gene , reporter gene , genetics , gene expression , regulation of gene expression
Summary Expression studies utilizing the regA promoters, fused in tandem or separately to promoterless reporter genes, indicated that regA is transcribed from two promoters (P1 and P2). Both promoters can act independently. Expression from the P1 promoter is not affected by the iron content of the medium. Expression from the P2 promoter is tightly regulated by iron.