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Regulation of bacterial gene expression by metal–protein complexes
Author(s) -
Hennecke H.
Publication year - 1990
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.1990.tb00538.x
Subject(s) - biology , repressor , gene , regulation of gene expression , gene expression , function (biology) , microbiology and biotechnology , dna binding protein , genetics , transcription factor
Summary Metal ions are essential cofactors in several transacting bacterial gene regulators. Upon binding of the metal, the receptor proteins act either as repressors of gene expression or, in other systems, as transcriptional activators. Other metal‐dependent regulatory proteins may function, directly or indirectly, as sensors of the cellular oxygen status, and may even be mediators in light‐responsive gene regulation.