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RNA polymerase heterogeneity in Streptomyces coelicolor A3(2)
Author(s) -
Buttner M. J.
Publication year - 1989
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.1989.tb00151.x
Subject(s) - streptomyces coelicolor , biology , sigma factor , rna polymerase , gene , genetics , streptomyces , transcription (linguistics) , escherichia coli , computational biology , bacteria , mutant , linguistics , philosophy
Summary Recent genetic and biochemical experiments have revealed the existence of at least seven different Sigma factors in Streptomyces coelicolor and demonstrated a role for alternative sigma factors in the control of differentiation and also in the transcription of primary metabolic genes. S. coelicolor has four genes predicted to encode sigma factors that are very closely related to the σ 70 polypeptide of Escherichia coli.