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Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone
Author(s) -
WANG LIUYANG,
LUZYNSKI KEN,
POOL JOHN E.,
JANOUŠEK VÁCLAV,
DUFKOVÁ PETRA,
VYSKOČILOVÁ MARTINA M.,
TEETER KATHERINE C.,
NACHMAN MICHAEL W.,
MUNCLINGER PAVEL,
MACHOLÁN MILOŠ,
PIÁLEK JAROSLAV,
TUCKER PRISCILLA K.
Publication year - 2011
Publication title -
molecular ecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.619
H-Index - 225
eISSN - 1365-294X
pISSN - 0962-1083
DOI - 10.1111/j.1365-294x.2011.05148.x
Subject(s) - hybrid zone , biology , linkage disequilibrium , house mouse , evolutionary biology , biological dispersal , disequilibrium , house mice , subspecies , selection (genetic algorithm) , haplotype , genetics , ecology , genetic variation , population , gene flow , gene , allele , medicine , demography , artificial intelligence , sociology , computer science , ophthalmology
Theory predicts that naturally occurring hybrid zones between genetically distinct taxa can move over space and time as a result of selection and/or demographic processes, with certain types of hybrid zones being more or less likely to move. Determining whether a hybrid zone is stationary or moving has important implications for understanding evolutionary processes affecting interactions in hybrid populations. However, direct observations of hybrid zone movement are difficult to make unless the zone is moving rapidly. Here, evidence for movement in the house mouse Mus musculus domesticus × Mus musculus musculus hybrid zone is provided using measures of LD and haplotype structure among neighbouring SNP markers from across the genome. Local populations of mice across two transects in Germany and the Czech Republic were sampled, and a total of 1301 mice were genotyped at 1401 markers from the nuclear genome. Empirical measures of LD provide evidence for extinction and (re)colonization in single populations and, together with simulations, suggest hybrid zone movement because of either geography‐dependent asymmetrical dispersal or selection favouring one subspecies over the other.