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Susceptibility of Clostridium perfringens of animal origin to fifteen antimicrobial agents
Author(s) -
DUTTA G. N.,
DEVRIESE L. A.
Publication year - 1980
Publication title -
journal of veterinary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.527
H-Index - 60
eISSN - 1365-2885
pISSN - 0140-7783
DOI - 10.1111/j.1365-2885.1980.tb00487.x
Subject(s) - lincomycin , virginiamycin , tiamulin , microbiology and biotechnology , tetracycline , erythromycin , chloramphenicol , clostridium perfringens , bacitracin , furazolidone , biology , penicillin , antibiotics , bacteria , genetics
The minimal inhibitory concentrations of fifteen antibacterial agents were determined by agar‐dilution method against 121 strains of Clostridium perfringens isolated from pigs, cattle and poultry. All strains, regardless of host of origin, were susceptible to avoparcin, furazolidone, monensin, nitrovin, penicillin G, ronidazole and tiamulin and resistant to flavomycin. Poultry strains were also susceptible to carbadox, chloramphenicol, erythromycin and virginiamycin. Bacitracin‐resistant poultry strains were susceptible to all tested antibacterial agents except tetracycline, but the bacitracin‐resistant cattle strains were polyresistant. Porcine strains were susceptible to bacitracin and bovine strains to carbadox. Carbadox‐resistant porcine strains were resistant to erythromycin, lincomycin and tetracycline and susceptible to chloramphenicol. Resistance to erythromycin was associated with resistance to lincomycin. High level erythromycin‐lincomycin‐resistant strains were susceptible to virginiamycin, but the intermediate level erythromycin‐lincomycin‐resistant cattle strains were resistant to virginiamycin. Resistance to chloramphenicol or erythromycin‐lincomycin was always associated with resistance to tetracycline but the reverse was not always true.