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The disposition and excretion of ethanol by the horse
Author(s) -
CHAPMAN D. I.,
RUDRAM D. A.
Publication year - 1978
Publication title -
journal of veterinary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.527
H-Index - 60
eISSN - 1365-2885
pISSN - 0140-7783
DOI - 10.1111/j.1365-2885.1978.tb00342.x
Subject(s) - ethanol , urine , excretion , saliva , horse , chemistry , body weight , oral administration , gastrointestinal tract , venous blood , disposition , medicine , zoology , biochemistry , biology , psychology , paleontology , social psychology
The disposition and excretion of ethanol in horses has been studied after oral administration. Ethanol was rapidly absorbed from the gastrointestinal tract. The highest concentration of ethanol in blood and in parotid saliva occurred within 1 h of administration. The concentrations were dose dependent. The mean rate of disappearance of ethanol from blood was 6.3 mg/100 ml/h. The ratio of the concentration of ethanol in parotid saliva to that in venous blood was 1.16:1. The mean rate of elimination was 51 mg/kg body weight/h. The proportion of ethanol excreted in the urine was 0.7% of the dose.