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Self‐perceived oral health and salivary proteins in children with type 1 diabetes
Author(s) -
JAVED F.,
SUNDIN U.,
ALTAMASH M.,
KLINGE B.,
ENGSTRÖM PE.
Publication year - 2009
Publication title -
journal of oral rehabilitation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.991
H-Index - 93
eISSN - 1365-2842
pISSN - 0305-182X
DOI - 10.1111/j.1365-2842.2008.01895.x
Subject(s) - saliva , medicine , diabetes mellitus , type 2 diabetes , type 1 diabetes , dry mouth , gastroenterology , oral health , immunoglobulin a , endocrinology , antibody , immunoglobulin g , immunology , dentistry
Summary The aim was to validate self‐perceived oral health with salivary IgG as an inflammatory parameter in children with type 1 diabetes. Unstimulated whole saliva samples were collected from 36 children with well controlled and 12 with poorly controlled type 1 diabetes and 40 non‐diabetic children (Controls). Salivary flow rate, random blood glucose level, salivary protein concentration and immunoglobulin A and G levels were recorded using standard techniques. Data concerning oral health and diabetes status were collected. Self‐perceived gingival bleeding (bleeding gums), bad breath and dry mouth were higher in diabetic children when compared with those in controls ( P < 0·05). Gingival bleeding was frequently perceived by children with poorly controlled compared to well‐controlled type 1 diabetes ( P < 0·05) and controls ( P < 0·001). Bad breath was common perceived by children with poorly controlled compared to well‐controlled type 1 diabetes ( P < 0·05) and controls ( P < 0·0001). Salivary flow rate was lower in the diabetic children compared to controls ( P < 0·01) with no difference between children with poorly controlled and well‐controlled type 1 diabetes. Salivary IgG per mg protein concentration was higher in the diabetics when compared with the control group ( P < 0·0001). IgG per mg protein levels were also higher in children with poorly controlled when compared with well‐controlled type 1 diabetes ( P < 0·05). There was no difference in IgA per mg protein and total protein concentrations between children with poorly controlled and well‐controlled type 1 diabetes. Self‐perceived gingival bleeding and salivary IgG per mg protein concentration were increased in children with type 1 diabetes compared with controls. These variables were also increased in children with poorly controlled compared with well‐controlled type 1 diabetes.