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Permeability of biological and synthetic molecules through dentine
Author(s) -
HANKS C.T.,
WATAHA J.C.,
PARSELL R.R.,
STRAWN S.E.,
FAT J.C.
Publication year - 1994
Publication title -
journal of oral rehabilitation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.991
H-Index - 93
eISSN - 1365-2842
pISSN - 0305-182X
DOI - 10.1111/j.1365-2842.1994.tb01162.x
Subject(s) - molecule , chemistry , permeability (electromagnetism) , aqueous solution , hydrogen peroxide , fluorescein , diffusion , ethanol , biophysics , chemical engineering , organic chemistry , fluorescence , biochemistry , membrane , physics , quantum mechanics , biology , thermodynamics , engineering
Summary The diffusion through dentine by a number of biological and synthetic molecules, including resins and dyes, is reported. In vitro measurements were derived by experiments with a modified ‘split‐chamber device’. Diffusion was found to be indirectly proportional to dentine thickness for all molecules. Permeability of water‐soluble molecules and ethanol‐soluble molecules was proportional to the molecular weights, except for fluorescein, hydrogen peroxide (H 2 O 2 ) and urethane dimethacrylate. The resin components tested are not soluble enough in an aqueous medium to diffuse through 0.5 mm dentine at sufficient concentrations to cause cytotoxicity to pulpal cells.