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Stem Cells, Hormones and Pituitary Adenomas
Author(s) -
Levy Andy
Publication year - 2008
Publication title -
journal of neuroendocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.062
H-Index - 116
eISSN - 1365-2826
pISSN - 0953-8194
DOI - 10.1111/j.1365-2826.2007.01621.x
Subject(s) - hormone , medicine , endocrinology , pituitary hormones , pituitary gland , pathogenesis , biology , cell , adenoma , cell division , genetics
Summary We still do not understand the pathogenesis of the majority of pituitary adenomas or why, once formed, their behaviour tends to be so benign. Understanding trophic activity in the normal pituitary may be the key. Despite the fact that changes in indices of cell division and programmed cell death that are too small to measure can produce highly significant fluxes in cell populations, little by little, the fascinating patterns of integrated responses of pituitary cells to hormonal stimuli are now being revealed.