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Co‐registered spectrally encoded confocal microscopy and optical frequency domain imaging system
Author(s) -
KANG D.K.,
SUTER M.J.,
BOUDOUX C.,
YACHIMSKI P.S.,
PURICELLI W.P.,
NISHIOKA N.S.,
MINOKENUDSON M.,
LAUWERS G.Y.,
BOUMA B.E.,
TEARNEY G.J.
Publication year - 2010
Publication title -
journal of microscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 111
eISSN - 1365-2818
pISSN - 0022-2720
DOI - 10.1111/j.1365-2818.2010.03367.x
Subject(s) - confocal microscopy , confocal , microscopy , optical coherence tomography , optical sectioning , optics , materials science , optical microscope , frequency domain , endomicroscopy , resolution (logic) , biomedical engineering , medicine , physics , computer science , artificial intelligence , computer vision , scanning electron microscope
Summary Spectrally encoded confocal microscopy and optical frequency domain imaging are two non‐contact optical imaging technologies that provide images of tissue cellular and architectural morphology, which are both used for histopathological diagnosis. Although spectrally encoded confocal microscopy has better transverse resolution than optical frequency domain imaging, optical frequency domain imaging can penetrate deeper into tissues, which potentially enables the visualization of different morphologic features. We have developed a co‐registered spectrally encoded confocal microscopy and optical frequency domain imaging system and have obtained preliminary images from human oesophageal biopsy samples to compare the capabilities of these imaging techniques for diagnosing oesophageal pathology.