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Positron emission tomography—a new technique for studies of the central nervous system
Author(s) -
Eriksson Lars,
Dahlbom Magnus,
Widén Lennart
Publication year - 1990
Publication title -
journal of microscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 111
eISSN - 1365-2818
pISSN - 0022-2720
DOI - 10.1111/j.1365-2818.1990.tb02968.x
Subject(s) - positron emission tomography , brain positron emission tomography , central nervous system , tomography , positron , nuclear medicine , physics , neuroscience , medical physics , medicine , preclinical imaging , psychology , optics , nuclear physics , biology , microbiology and biotechnology , in vivo , electron
SUMMARY Positron emission tomography (PET) has become an important tool to study the central nervous system. Examples of such studies are cerebral blood flow and metabolism and determination of receptor characteristics of the brain. In the following the basic principles and the physics behind PET are given. Different aspects are discussed such as detector design, image reconstructions and data analyses. Since quantification is essential in PET, data have to be corrected for absorption, scatter and random coincidences. These corrections and their influence on image data are discussed. A review of state‐of‐the‐art PET research of the brain is given.