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The development of biological preparative techniques for light microscopy, 1839–1989
Author(s) -
Bracegirdle Brian
Publication year - 1989
Publication title -
journal of microscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 111
eISSN - 1365-2818
pISSN - 0022-2720
DOI - 10.1111/j.1365-2818.1989.tb02892.x
Subject(s) - nanotechnology , perfection , microtome , biochemical engineering , materials science , engineering , optics , philosophy , physics , epistemology
SUMMARY The development of techniques of preparing biological material for microscopical observation is summarized, with much greater emphasis being given to the introduction and establishment of the various techniques, largely in the nineteenth century, than to their perfection and extremely widespread use in the twentieth century. The development of the microtome as an instrument of the greatest importance is summarized and an assessment is made of the impact of preparative techniques on the development of the medical sciences.