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Immuno‐ and enzyme‐histo/cytochemical analysis of resin sections and cell suspensions: a comprehensive diagnosis of bone marrow on a single aspiration sample
Author(s) -
Sandt M. M.,
Herman C. J.,
Lindeman J.
Publication year - 1986
Publication title -
journal of microscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 111
eISSN - 1365-2818
pISSN - 0022-2720
DOI - 10.1111/j.1365-2818.1986.tb02778.x
Subject(s) - bone marrow , pathology , biopsy , pathological , bone marrow aspirate , cell , medicine , chemistry , biochemistry
SUMMARY A protocol is described in which a single bone marrow aspiration specimen is used to prepare resin sections and cell suspensions. Using this protocol, a full battery of morphological, enzyme‐histochemical, immuno‐histochemical and cyto‐pathological techniques can be applied. This allows a definitive bone marrow diagnosis to be established without resorting to bone marrow biopsy in the majority of patients.