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A method for the preparation of cerebral blood vessels
Author(s) -
Grocki Kurt,
Dermietzel Rolf
Publication year - 1984
Publication title -
journal of microscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 111
eISSN - 1365-2818
pISSN - 0022-2720
DOI - 10.1111/j.1365-2818.1984.tb00469.x
Subject(s) - fibrin , ultrastructure , fibrinogen , electron microscope , thrombin , perfusion , blood vessel , pathology , chemistry , biomedical engineering , anatomy , biophysics , medicine , biology , biochemistry , platelet , optics , physics , immunology
SUMMARY Elements of the cerebral vascular system of the rat have been prepared by simultaneous perfusion with fibrinogen and thrombin. The resulting fibrin fills and serves to support the vessels which can then easily be excised from the brain and prepared for light and electron microscopy. The structure and ultrastructure of cerebral blood vessels is well preserved by this technique.