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High voltage electron microscopy of cellular changes in the wet state
Author(s) -
Clarke J. A.,
Ward P. R.,
Salsbury A. J.
Publication year - 1973
Publication title -
journal of microscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 111
eISSN - 1365-2818
pISSN - 0022-2720
DOI - 10.1111/j.1365-2818.1973.tb03791.x
Subject(s) - transmission electron microscopy , electron microscope , phase contrast microscopy , microscopy , bacteria , materials science , microscope , biophysics , chemistry , optics , nanotechnology , biology , physics , genetics
SUMMARY Red blood cells and bacteria have been viewed under the high voltage transmission electron microscope, using a controlled environment chamber. Red cell changes on introduction of an agglutinating serum into the environment and bacterial changes on addition of an antibiotic, were observed. The results are compared with those obtained by phase contrast light microscopy and the potentialities of the system discussed.