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Lanthanum as an intracellular stain
Author(s) -
Bannister L. H.
Publication year - 1972
Publication title -
journal of microscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 111
eISSN - 1365-2818
pISSN - 0022-2720
DOI - 10.1111/j.1365-2818.1972.tb01042.x
Subject(s) - intracellular , endoplasmic reticulum , microtubule , stain , microbiology and biotechnology , staining , lanthanum , negative stain , substructure , mitochondrion , chemistry , biophysics , biology , electron microscope , physics , genetics , inorganic chemistry , structural engineering , engineering , optics
SUMMARY In mouse and fish olfactory mucosæ, lanthanum has been found to penetrate various intracellular components of cells including the endoplasmic reticulum, mitochondria, microvilli, microtubules and cilia, outlining their substructure in negative contrast when seen in sectioned specimens. Structural details approaching those seen in disrupted negatively stained material were observed in sections, suggesting that intracellular lanthanum staining may prove a useful tool in morphological studies.