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New observations on the role of the erythrocyte in hæmostasis
Author(s) -
FORD BRIAN J.
Publication year - 1965
Publication title -
journal of the royal microscopical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 111
eISSN - 1365-2818
pISSN - 0368-3974
DOI - 10.1111/j.1365-2818.1965.tb02143.x
Subject(s) - coagulation , reticulum , consolidation (business) , occlusion , chemistry , biophysics , anatomy , biology , endoplasmic reticulum , microbiology and biotechnology , medicine , surgery , accounting , business
SYNOPSIS Classical expositions of the theory of blood coagulation hold that consolidation of the fibrinous reticulum is due to the mechanical enmeshment of erythrocytes within it. Studies of coagulating blood by dark‐ground microscopy have revealed the attachment of submicroscopic threads to the erythrocyte walls at precise loci: it is postulated that the formation of captive cells ( penderocytes ) leads to haemostatic occlusion and the total retention of erythrocytes within the contracting coagulum. Filmed records of the phenomena provide distinction between true penderocytes, those erythrocytes attached at random, and occasional enmeshed cells.