Premium
RECENT DISCOVERIES CONCERNING MITOCHONDRIA AND GOLGI APPARATUS AND THEIR SIGNIFICANCE IN CELLULAR PHYSIOLOGY
Author(s) -
Bourne Geoffrey H.
Publication year - 1950
Publication title -
journal of the royal microscopical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 111
eISSN - 1365-2818
pISSN - 0368-3974
DOI - 10.1111/j.1365-2818.1950.tb04444.x
Subject(s) - golgi apparatus , mitochondrion , citric acid cycle , biochemistry , microbiology and biotechnology , biology , enzyme , cell , metabolism , chemistry
SYNOPSIS. Mitochondria Recent researches have shown that mitochondria contain a high percentage of a number of enzymes which play an important part in the aerobic metabolism of the cell. The mitochondria therefore rise to importance as the major centres of cell respiration. The fact that many of these enzymes are constituents of the Krebs tricarboxylic acid cycle‐a cycle which has been described as the meeting point of protein, fat, and carbohydrate metabolism‐indicates that mitochondria may in addition be concerned both with breakdown of protein and fat as well as carbohydrate and with the synthesis of these three substances. Golgi apparatus A mass of evidence now supports the conception of the Golgi apparatus as being composed of lipo‐protein spheres which possess unusual capabilities of segregation for a variety of substances. It is suggested that the primary function of these spheres is to protect the cell by segregating noxious substances. In secretory cells this segregating ability is used to accumulate secretory products which have been synthesized by the mitochondria.