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Management of acute coronary syndrome: achievements and goals still to pursue. Novel developments in diagnosis and treatment
Author(s) -
Boden H.,
van der Hoeven B. L.,
Karalis I.,
Schalij M. J.,
Jukema J. W.
Publication year - 2012
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.2012.02533.x
Subject(s) - medicine , antithrombotic , intensive care medicine , acute coronary syndrome , disease , ischaemic heart disease , risk factor , myocardial infarction , cardiology
. Boden H, van der Hoeven BL, Karalis I, Schalij MJ, Jukema JW (Leiden University Medical Center, Leiden, The Netherlands). Management of acute coronary syndrome: achievements and goals still to pursue. Novel developments in diagnosis and treatment (Review). J Intern Med 2012; 271 : 521–536. Acute coronary syndromes contribute a substantial part of the global disease burden. To realize a reduction in mortality and morbidity, the management of patients with these conditions involves the integration of several different approaches. Timely delivery of appropriate care is a key factor, as the beneficial effect of reperfusion is greatest when performed as soon as possible. Innovations in antithrombotic therapy have also contributed significantly to improvements in the prevention of ischaemic complications. However, with the use of such treatment, an increase in the risk of bleeding is inevitable. Therefore, the greatest challenge is now to obtain an optimal balance between the prevention of ischaemic complications and the risk of bleeding. In this regard, identification of patients at highest risk of either one is essential.