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The membrane protein universe: what's out there and why bother?
Author(s) -
Von Heijne G.
Publication year - 2007
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.2007.01792.x
Subject(s) - membrane protein , vesicle associated membrane protein 8 , integral membrane protein , membrane transport protein , aquaporin , peripheral membrane protein , medicine , microbiology and biotechnology , membrane , biology , biochemistry
. Chances are that you have come across membrane proteins many times in your professional life: ion channels, aquaporins, G‐protein‐coupled receptors, drug resistance proteins. But it is also quite likely that you have never bothered to think about what the implications are of being a membrane protein, as opposed to a soluble protein. What is special about membrane proteins in terms of structure and function, how many membrane proteins are out there, how are they made in the cell? Welcome to the membrane protein universe!