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Calcium and vitamin D in the prevention and treatment of osteoporosis – a clinical update
Author(s) -
BOONEN S.,
VANDERSCHUEREN D.,
HAENTJENS P.,
LIPS P.
Publication year - 2006
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.2006.01655.x
Subject(s) - medicine , vitamin d and neurology , osteoporosis , calcium , calcium supplementation , vitamin , endocrinology , intensive care medicine
. Combined calcium and vitamin D supplementation is an essential component of the management of osteoporosis, supported by a strong scientific rationale. The types of individuals who should receive calcium and vitamin D supplements are those: (i) patients with documented osteoporosis receiving antiresorptive or anabolic treatment; (ii) patients receiving glucocorticoids; and (iii) individuals with or at high risk of calcium and/or vitamin D insufficiencies, in particular older women and men. This article describes the evidence base that supports targeting these groups. Benefits are most apparent when 800 IU day −1 vitamin D is complemented with a dose of 1000–1200 mg day −1 elemental calcium. Compliance is also key to optimizing clinical efficacy.