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Carbimazole induced eosinophilic granulomatous vasculitis localized to the stomach
Author(s) -
SÈVE P.,
STANKOVIC K.,
MICHALET V.,
VIAL T.,
SCOAZEC J.Y.,
BROUSSOLLE C.
Publication year - 2005
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.2005.01525.x
Subject(s) - medicine , carbimazole , stomach , vasculitis , eosinophilic , churg strauss syndrome , pathology , dermatology , disease , graves' disease
. Vasculitis associated with anti‐neutrophil cytoplasmic antibodies has been reported in patients treated with anti‐thyroid drugs and especially propylthiouracil. We report here a case of granulomatous eosinophilic vasculitis mimicking gastric neoplasm and peripheral eosinophilia in a 27‐year‐old man who was treated with carbimazole for 5 months for Graves’ disease. Clinical and morphologic features resolved within 2 months after stopping the drug, suggesting a causative role for the drug. To our knowledge, this is the first biopsy‐proven granulomatous eosinophilic vasculitis associated with this drug.