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Thyrotoxic period paralysis: report of three cases and review of the literature.
Author(s) -
PAPADOPOULUS K. I.,
DIEP T.,
CLELAND B.,
LUNN N. W.
Publication year - 1997
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1997.tb00011.x
Subject(s) - thyrotoxic periodic paralysis , etiology , medicine , periodic paralysis , pediatrics , paralysis , weakness , epidemiology , hypokalemic periodic paralysis , differential diagnosis , graves' disease , surgery , psychiatry , disease , pathology
. Papadopoulos KI, Diep T, Cleland B. Lunn N W (Fairfield Hospital, Wetherill Park, Australia) Thyrotoxic periodic paralysis: report of three cases and review of the literature (Case report. Thyrotoxic periodic paralysis (TPP) is a neuromuscular disoder that, in a global perspective, only affects a small percentage of patients with thyrotoxicosis of any aetiology, but is a fairly common phenomenon in Asian populations where it predominantly ouucrs in males. Three typical cases are presented here. All three patients were Asian males, one being the first Laotian patient reported to have this disorder. In one case prodromal symptoms of TPP occurred during a relapse of the thyrotoxicosis. The epidemiology, clinical manifestations, aetiology and treatment of this relatively rare condition are discussed. As oriental races are now frequently ecnountered in the Western world, it is imperative that TPP is included in the differential diagnosis of muscle weakness in order to avoid the life‐threatening complications of hypokalaemia and thyrotoxicosis.