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Improvement of sleep apnoea due to acromegaly during short‐term treatment with octreotide
Author(s) -
LEIBOWITZ G.,
SHAPIRO M. S.,
SALAMEH M.,
GLASER B.
Publication year - 1994
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1994.tb01288.x
Subject(s) - acromegaly , medicine , octreotide , somatostatin analogue , sleep (system call) , excessive daytime sleepiness , somatostatin , sleep disorder , insomnia , hormone , growth hormone , psychiatry , computer science , operating system
. Two acromegalic patients suffering from severe obstructive sleep apnoea syndrome were treated with the long‐acting somatostatin analogue octreotide. Daytime sleepiness and fatigue improved within a few days. Repeat sleep studies performed after octreotide treatment revealed more confluent sleep with a shorter duration of sleep apnoea. Nocturnal hypoxaemia improved in one patient. Octreotide might be an effective noninvasive treatment for sleep apnoea of acromegaly.