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Paralytic ileus as a result of diltiazem treatment
Author(s) -
MANTZOROS C. S.,
PRABHU A. S.,
SOWERS J. R.
Publication year - 1994
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1994.tb01270.x
Subject(s) - diltiazem , medicine , contractility , angina , cardiology , calcium channel blocker , inotrope , nifedipine , calcium , ileus , ischemia , calcium channel , anesthesia , gastroenterology , myocardial infarction
. Diltiazem is a widely used calcium channel blocker, and has been found to be effective in the treatment of hypertension, stable, variant and unstable angina, as well as oesophageal spasm. Calcium channel antagonists have been shown to diminish the contractility of gut smooth muscle, but have not as yet been reported to cause clinically significant inhibition of gut motility when used alone. We report a case of reversible functional intestinal obstruction, immediately following diltiazem treatment in a patient with ischaemic heart disease.