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Hypercalcaemic crisis after excessive topical use of a vitamin D derivative
Author(s) -
Hoeck H. C.,
Laurberg G.,
Laurberg P.
Publication year - 1994
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1994.tb01074.x
Subject(s) - medicine , calcipotriol , limiting , vitamin d and neurology , dermatology , calcium , intensive care medicine , mechanical engineering , engineering , psoriasis
. Topical application of the vitamin D analogue calci‐potriol has been found to be of clinical value in the treatment of dermatological disorders. This is considered to be safe with respect to alterations in calcium homeostasis. We report a 17‐year‐old female patient who developed hypercalcaemic crisis after excessive use of calcipotriol for ichthyosis. The clinical condition and serum calcium improved after cessation of calciprotiol treatment and rehydration with intravenous fluids and electrolytes. The case emphasizes the importance of limiting the topical use of calcipotriol as recommended by the manufacturer.