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Supraventricular tachycardia, right atrial pressure, atrial natriuretic peptide and polyuria—a necessary sequence ?
Author(s) -
TAN S. Y.,
NOLAN J.,
CRAIG K.,
SWAINSON C. P.
Publication year - 1993
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1993.tb00693.x
Subject(s) - medicine , cardiology , atrial natriuretic peptide , supraventricular tachycardia , polyuria , atrial tachycardia , tachycardia , atrial fibrillation , endocrinology , catheter ablation , diabetes mellitus
. The release of atrial natriuretic peptide (ANP) may be stimulated by tachycardia and the evidence from human studies suggests that this is mediated by a rise in atrial pressure. However, animal experiments suggest that tachycardia can by itself increase ANP levels without increasing right atrial pressure (RAP). We report here the case of a healthy volunteer who had supraventricular tachycardia (SVT) whilst participating in a study evaluating the relationship between changes in RAP and changes in ANP. The ANP levels rose following the SVT but there was no rise in RAP, suggesting that heart rate can modulate ANP levels without changes in RAP as has been shown in animal experiments.