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Effect of coffee on ambulatory blood pressure in patients with treated hypertension
Author(s) -
EGGERTSEN R.,
ANDREASSON Å.,
HEDNER T.,
KARLBERG B. E.,
HANSSON L.
Publication year - 1993
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1993.tb00683.x
Subject(s) - medicine , caffeine , blood pressure , ambulatory blood pressure , ambulatory , heart rate , placebo , regimen , plasma renin activity , prehypertension , renin–angiotensin system , cardiology , endocrinology , anesthesia , alternative medicine , pathology
. Effects of caffeine on ambulatory blood pressure, heart rate, renin‐angiotensin system, and ANP were studied in patients treated for mild to moderate hypertension in a randomized, double‐blind, placebo‐controlled, cross‐over trial comparing 2 weeks of caffeine‐free diet with 2 weeks of regular coffee use. Twenty‐three patients (13 men; aged 28–74 years) with treated, mild to moderate essential hypertension and a regular intake of 3–4 cups of coffee daily completed the study. Mean 24‐h, day‐ or night‐time ambulatory blood pressure and heart rate were not different between regimens. Nor were there any effects on the renin‐angiotensin system while ANP was significantly increased during caffeine intake. Compliance of the dietary regimen was excellent as assessed by serum caffeine concentration measurements. We conclude that habitual coffee drinking did not influence the 24‐h blood pressure profiles or cardiovascular hormones in treated hypertensives.