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Stroke morbidity in patients treated for hypertension—The Skaraborg Hypertension Project
Author(s) -
LINDBLAD U.,
RÅSTAM L.,
RANSTAM J.
Publication year - 1993
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1993.tb00668.x
Subject(s) - medicine , stroke (engine) , confidence interval , incidence (geometry) , population , cohort , relative risk , body mass index , cohort study , surgery , mechanical engineering , physics , environmental health , optics , engineering
. Stroke incidence was analysed in a Swedish cohort of male (n = 1428) and female ( n = 1812) hypertensive patients in comparison with age‐ and sex‐matched population controls (1:1) and with normotensive untreated subjects (1249 men and 1247 women). Mean follow‐up was 8.3 years. Patients were aged 40–69 at the start of follow‐up in 1977–1981. Relative risks (95% confidence interval [CI]) for stroke morbidity were 1.63 (1.16, 2.29) for men and 1.40 (0.94, 2.09) for women compared to population controls. Corresponding figures for stroke mortality were 1.96 (1.01–3.82) and 1.48 (0.71–3.06). Compared to the normotensive sample with adjustment for smoking and body mass index relative risks for stroke morbidity were 3.07 (1.96–4.80) for men and 2.56 (1.46–4.51) for women. The prognosis of treated hypertension with respect to stroke is better than anticipated from previous studies, a fact that should be considered when treatment guidelines are developed.