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Acute and chronic pancreatic disease associated with Yersinia enterocolitica infection: a Norwegian 10‐year follow‐up study of 458 hospitalized patients
Author(s) -
SAEBØ A.,
LASSEN J.
Publication year - 1992
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1992.tb00970.x
Subject(s) - medicine , yersinia enterocolitica , pancreatitis , diabetes mellitus , acute pancreatitis , etiology , gastroenterology , endocrinology , genetics , bacteria , biology
. During the period 1974–1983, Yersinia enterocolitica infection was diagnosed in 458 hospitalized patients by antibody response or isolation of the micro‐organism. Eight (1.75%) patients showed signs of acute pancreatitis with elevated serum or urine levels of amylase; two patients had acute insulin‐dependent diabetes. The patients were followed up for 4–14 years (until 1987). Four patients were readmitted with chronic pancreatitis, and one with acute pancreatitis. Diabetes developed in two males and nine females; in seven cases this was associated with chronic conditions of possible autoimmune aetiology. In 1987 a significantly higher than expected prevalence of diabetes was demonstrated among female subjects aged 30–54 years. Yersinia enterocolitica infection constitutes a differential diagnosis in acute pancreatitis, and might be related to the development of chronic pancreatitis and diabetes.