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Paraproteinaemia in relatives of patients with primary acquired agammaglobulinaemia
Author(s) -
HABASHI H.,
HEPPLESTON A.,
WINTER J.
Publication year - 1991
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1991.tb00444.x
Subject(s) - medicine , dyscrasia , genetic predisposition , immunology , paraproteinemias , immunopathology , antibody , pathology , monoclonal , disease , plasma cell , monoclonal antibody
. Two instances of the unusual familial association of severe primary acquired hypogammaglobulinaemia and paraproteinaemia are described, and previous reports of familial immunoglobulin dyscrasias are discussed. Our observations lend further support to the possible existence of a genetic predisposition to these disorders.