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Serum lipid and apolipoprotein levels in non‐hypertensive lean NIDDM patients
Author(s) -
IKEDA T.,
OCHI H.,
OHTANI I.,
FUJIYAMA K.,
HOSHINO T.,
TANAKA Y.,
TAKEUCHI T.,
MASHIBA H.
Publication year - 1991
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1991.tb00420.x
Subject(s) - medicine , endocrinology , triglyceride , diabetes mellitus , apolipoprotein b , lipid metabolism , body mass index , cholesterol
. To determine the possible role of a glycaemic control in lipid metabolism in non‐insulin‐dependent diabetes mellitus (NIDDM) patients, serum lipid and apolipoprotein levels were measured in well‐controlled and poorly controlled lean NIDDM without proteinuria and hypertension. A sample of 96 lean NIDDM patients (body mass index < 25 kg m −2 in men and < 27 kg m −2 in women) were divided into two groups: group I, where the HbA 1c concentration had been < 6% for the previous 3 months, and group II, where the HbA 1c concentration had been > 8% for the previous 3 months. Serum total cholesterol, triglyceride, and HDL‐cholesterol levels showed no significant differences between groups I and II. Furthermore, serum levels of apolipoproteins AI, AII, B, CII, CIII, and E did not differ significantly between groups I and II. These results suggest that glycaemic control did not influence lipid metabolism in lean NIDDM patients.