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The predictive capability of the glycaemic response to spaghetti in non‐insulin dependent (NIDDM) and insulin dependent (IDDM) diabetic subjects
Author(s) -
RASMUSSEN O.,
GREGERSEN S.,
HERMANSEN Dr.K.
Publication year - 1990
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1990.tb00201.x
Subject(s) - medicine , insulin , insulin response , diabetes mellitus , endocrinology , plasma glucose
. To evaluate the predictive capability of the postprandial blood glucose response after consumption of a starch‐rich meal, we compared the glycaemic effects of spaghetti (60 g) taken alone and with bolognese sauce (167 g). The study was carried out in both NIDDM ( n = 6) and IDDM ( n = 6) subjects. The latter had achieved normoglycaemia 120 min prior to the test meal by means of an artificial pancreas (Biostator®) which provided constant insulinaemia during the observation period of 4 h. We found that the areas of blood glucose (above basal) were identical irrespective of whether spaghetti was taken alone or as part of a mixed meal in both NIDDM (484 ± 1 54 mmol l −1 240 min −1 vs. 393 ± 126 mmol l −1 240 min −1 ) and IDDM subjects (6.10 ± 143 mmol l −1 240 min −1 vs. 770 ± 135 mmol l −1 240 min −1 ). The insulin levels were identical in the IDDM diabetics. By contrast, the mixed meal caused a more marked insulinaemic response than spaghetti per se in the NIDDM subjects (3187 ± 637 mU l −1 240 min −1 vs. 1940 ± 235 mU l −1 240 min −1 ; P < 0.05). In conclusion, the predictive capability of the glycaemic response to spaghetti was good in both IDDM and NIDDM diabetic subjects, at least under the conditions of the present study.