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Long‐term nopharmacological treatment for mild to moderate hypertension
Author(s) -
JULA A.,
RÖNNEMAA T.,
RASTAS M.,
KARVETTI R.L.,
MÄKI J.
Publication year - 1990
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1111/j.1365-2796.1990.tb00180.x
Subject(s) - medicine , blood pressure , diastole , endocrinology , blood lipids , cholesterol , cardiology
. Ninety‐one middle‐aged men and women with untreated mild hypertension were allocated to a nopharmacological treatment group or to a control group. Members of the treatment group were instructed to reduce daily sodium intake to < 70 mmol, to reduce the intake of saturated fat, to lose weight if necessary and to perform regular physical exercise and relaxation training. Adherence to and effects of the programme on blood pressure and serum lipids were monitored for 12 months. In the treatment group, daily sodium excretion decreased to and remained at 50% of its original level ( P < 0.001), and there was a significant reduction in saturated fat intake. The average weight reduction was modest. Adherence to physical exercise and relaxation training regimens was poor. The net decreases (difference in changes between treatment and control group) in blood pressure were greatest during the first 3 months: in men the decrease in systolic blood pressure was 11.3 mmHg ( P < 0.001) and in diastolic blood pressure 8.3 mmHg ( P < 0.001); in women the decrease in systolic blood pressure was 10.8 mmHg ( P < 0.01) and in diastolic blood pressure 6.4 mmHg ( P < 0.01). However, this decrease diminished during the last 3 months to approximately one half owing to blood pressure reduction in controls. Low density lipoprotein cholesterol levels decreased significantly in treated men and women.